Our paper reporting carboxylate-directed addition of aromatic C-H Bond to aromatic aldehyde catalyzed by Ru catalysts was published in ACS Catalysis (ACS).
「Carboxylate-directed Addition of Aromatic C-H Bond to Aromatic Aldehydes under Ruthenium Catalysis」Miura, Hiroki; Terashima, Sachie; Shishido, Tetsuya
ACS Catalysis, 2018, 8, 6246-6254, DOI:10.1021/acscatal.8b00680
We report that ruthenium complexes effectively catalyzed the carboxylate-directed addition of aromatic C-H bonds to aldehydes. The reactions of aromatic acids with a variety of aromatic aldehydes including unactivated ones proceeded efficiently to give the corresponding isobenzofuranone derivatives in high yields. The combination of ruthenium(II) complexes with tricyclohexylphosphine led to highly nucleophilic aryl-metal species, which enabled versatile [3 + 2] cycloaddition in the absence of a Lewis acid. This paper also demonstrates the application of supported ruthenium catalysts to the title reaction.
