飴山楓君が中心となって行った担持Au触媒による活性エステルの脱炭酸型シリル化に関する研究成果がAdvanced Synthesis & Catalysis​​​​​​​誌 (Wiley)にAcceptされました。Our paper reporting harnessing supported gold nanoparticle as a single-electron transfer catalyst for decarboxylative cross-coupling was accepted in Advanced Synthesis & Catalysis​​​​​​​ (Wiley).

飴山楓君が中心となって行った担持Au触媒による活性エステルの脱炭酸型シリル化に関する研究成果がAdvanced Synthesis & Catalysis誌 (Wiley)にAcceptされました。Our paper reporting harnessing supported gold nanoparticle as a single-electron transfer catalyst for decarboxylative cross-coupling was accepted in Advanced Synthesis & Catalysis (Wiley).

 

「Harnessing Supported Gold Nanoparticle as a Single-Electron Transfer Catalyst for Decarboxylative Cross-Coupling」.

 

Hiroki Miura, Kaede Ameyama, Tetsuya Shishido

 

Advanced Synthesis & Catalysis, 2023, . DOI: 10.1002/adsc.202300462  [Highlighted as "VIP" (Very Important Publication)]

 

We found that gold nanoparticles function as single-electron　transfer catalysts to promote decarboxylative cross-coupling between N-hydroxy phthalimide esters and disilanes or diborons. A variety of disilanes coupled with alkyl radicals could be generated from N-hydroxy phthalimide esters via single-electron reduction by active carbon-supported gold nanoparticle catalysts to afford diverse alkylsilanes without the need for external bases. Furthermore, the present gold catalytic system was also effective for decarboxylative carbon–boron coupling to afford alkyl boronates. A detailed mechanistic investigation revealed that single-electron transfer mediated by supported gold nanoparticles enabled the generation of alkyl radical and silyl radical, thereby enabling radical cross-coupling. The reusability and environmentally friendly nature of supported gold catalyst as well as the scalability of the reaction system enable　the practical transformation of carboxylic acid derivatives into value-added organosilicon and organoboron compounds.